This sedating activity is sometimes used in managing conditions such as eczema where sleep maybe disturbed due to pruritus.
Sedating antihistamines also have significant antimuscarinic activity and should be used with caution in patients with prostatic hypertrophy, urinary retention and angle-closure glaucoma.
In fact, most over-the-counter sleep aids contain antihistamines.
These products are intended to be used for only two to three nights at a time, however, such as when stress, travel or other disruptions keep you awake.
They're also sometimes used to prevent motion sickness and as a short-term treatment for sleeping difficulties (insomnia).
Most antihistamines can be bought from pharmacies and shops, but some are only available on prescription.
Sedating antihistamines cause sedation as they are highly lipid soluble and readily cross the blood brain barrier.
It is sometimes used along with Vitamin B6 to stop morning sickness during pregnancy.
Doxylamine is one of the most powerful OTC sedatives in the U. Many patients taking doxylamine encounter dry mouth, nausea, and drowsiness.
Antihistamines can cause drowsiness, which might help you fall asleep for a few nights — but routine use of antihistamines for insomnia isn't recommended.
Antihistamines induce drowsiness by working against histamine, a chemical produced by the central nervous system.